Xanax, or alprazolam, is a very powerful benzodiazepine used to treat anxiety disorders and panic disorders and can even be used as a muscle relaxant during medical procedures. It was created to take the place of barbiturates believing benzos would be less addictive. However, this is far from the truth. It is extremely addictive when used long term. Xanax is the most commonly prescribed Benzodiazepine in the United States. According to the NIH:

Between 1996 and 2013, the number of adults who filled a benzodiazepine prescription increased by 67%, from 8.1 million to 13.5 million. In 2015, 23 percent of people who died of an opioid overdose also tested positive for benzodiazepines.

Benzodiazepines such as Xanax are not typically primary drugs that are abused. This means they are commonly used in combination with other drugs. They are commonly mixed with narcotic pain medications, alcohol, stimulants, and illegal opiates such as heroin.

Can You Potentiate Xanax?

Potentiation of Xanax

When a user mixes two or more different drugs at the same time, they heighten the risk of experiencing effects that are different than what they would feel taking a drug individually. There are different kinds of reactions a person will have depending on what is mixed together. The four major groups are:

  • Antagonism: This happens when one drug reduces the effect of another drug. For example, taking Xanax while taking cocaine at the same time will reduce the effects of both the cocaine and the Xanax taken.
  • Synergism: This happens when two or more drugs work jointly to produce a therapeutic effect.
  • Interactions: With a person, metabolism will occur in multiple places in the body and can either facilitate or slow down the elimination of the drug from one’s system.
  • Potentiation: Happens when the effects of one drug strengthen the effects of another drug. For instance, taking Xanax with alcohol will produce and enhancement of the depressant effects in both things that are taken.

The potentiation of Xanax occurs when a person abuses Xanax with other central nervous system depressants mixed in for a synergetic effect. This can include drugs like narcotic pain medications, alcohol, sedatives, cannabis, and other benzo products. When taken on their own, central nervous system depressants result in reduced blood pressure, heart rate, breathing rate, and reaction time that will result in effects such as poor coordination, poor balance, impaired reflexes, and impaired judgment. When taking central nervous system depressants with other depressants, you will potentiate these effects. Different potentiating effects are depending on the doses of each drug. It is important to know that the amount of a drug that can produce an overdose is decreased when combined with other central nervous system depressants.

Get Help Now With Xanax Addiction

If you or someone you love are ready to take the necessary steps to get sober, the best way to start is with a medically assisted detox process. Due to the brains rewiring after prolonged use, withdrawal symptoms can be extremely intense and even deadly when you abruptly stop. These symptoms include seizures, coma, hallucinations, muscle pain, and cramping, and even suicidal thoughts, to name a few. Medical detox is always recommended and your doctors will come up with the best plan for you to safely detox the benzos from your system.

Once you have detoxed, the best and safest option to get off of and stay off Benzodiazepines is by the use of one of the many treatment programs we offer at Recreate Life Counseling We offer many different treatment programs that provide therapeutic education and guidance for each individual to help them safely reintegrate into society. With the help of our team of therapists, we offer one on one, group therapy, as well as many other specialized options to fit each person’s needs. Benzodiazepine treatment requires a multi-layered approach for maximum success. We want to make sure you have the tools you need to avoid relapse in the real world.

Addiction isn’t an easy thing to face. Luckily you do not have to face it on your own. Our admissions counselors and professionals are available around the clock. We are ready to help you or a loved one overcome the disease of addiction. Now is the time to change your life. Let us help you do it.


  • What potentiate’s Xanax?
  • What chemicals potentiate benzodiazepines, antagonize them or have an adverse reaction when mixed?
  • What can cause a Xanax overdose?

Published on: 2020-04-25
Updated on: 2024-04-18